Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438329
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name synonims
N/A
Also known as
CD30
Gene name
TNFRSF8
Clone
CD30/412
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG2b, kappa
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
TNFRSF8; TNFRSF8; CD30; Ki-1; D1S166E; CD30; D1S166E
Tested applications:
ELISA (EIA), Flow Cytometry(FC/FACS, Immunofluorescence (IF), Immunohistology(IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
tumor necrosis factor receptor superfamily member 8 isoform 1; Tumor necrosis factor receptor superfamily member 8; tumor necrosis factor receptor superfamily member 8; Ki-1 antigen; CD30L receptor; cytokine receptor CD30; lymphocyte activation antigen CD30; tumor necrosis factor receptor superfamily, member 8; CD30L receptor; Ki-1 antigen; Lymphocyte activation antigen CD30; CD_antigen: CD30
Specificity and cross-reactivity
Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin's disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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