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- HMG1 (HMGB1, High Mobility Group, HMG Transcription Factor Box1, Amphoterin, Sulfoglucuronyl Carbohydrate Binding Protein, SBP-1, HMG3)
Product short description
Price:
575 EUR
Size:
100ug
Catalog no.:
GEN601562
Product detailed description
Clone
4C3
Concentration
N/A
Also known as
HMG1
Immunoglobulin isotype
IgG2a
Clonality
Monoclonal
Category
Antibodies
Tested applications:
Western Blot (WB)
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
HMGB1; HMGB1; HMG1; HMG3; SBP-1; HMG1; HMG-1
Gene name synonims
HMGB1; HMGB1; HMG1; HMG3; SBP-1; HMG1; HMG-1
Gene name
HMGB1; HMGB1; HMG1; HMG3; SBP-1; HMG1; HMG-1
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 50% glycerol.
Purification method
Affinity Purified by Protein A affinity chromatography.
Species reactivity
Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
high mobility group protein B1; High mobility group protein B1; high mobility group protein B1; HMG-1; Amphoterin; high-mobility group box 1; high mobility group protein 1; Sulfoglucuronyl carbohydrate binding protein; high-mobility group (nonhistone chromosomal) protein 1; high mobility group box 1; High mobility group protein 1
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity
Recognizes HMGB1 (HMG 1) at ~29kD, corresponding to the apparent molecular mass of high mobility group box 1 protein. Species Crossreactivity: human, mouse and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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