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- Caspase 8, Cleavage Site (Asp384) (FLICE, MASH, Mch5)
Product short description
Price:
603 EUR
Size:
100ul
Catalog no.:
GEN601687
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
3A52
Category
Antibodies
Clonality
Monoclonal
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Also known as
Caspase 8, Cleavage Site
Tested applications:
ELISA (EL/EIA), Western Blot (WB)
Purification method
Affinity Purified by immunoaffinity chromatography.
Other gene names
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Gene name synonims
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Gene name
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Form/Appearance
Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol, 0.02% sodium azide.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Specificity and cross-reactivity
Detects endogenous levels of the small subunit of caspase-8 resulting from cleavage at Asp384. Does not crossreact with full length caspase-8.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other names
caspase 8; Caspase-8; caspase-8; FADD-like ICE; OTTHUMP00000163717; OTTHUMP00000163720; OTTHUMP00000165062; OTTHUMP00000165063; OTTHUMP00000165064; OTTHUMP00000206552; MACH-alpha-1/2/3 protein; apoptotic protease Mch-5; MACH-beta-1/2/3/4 protein; apoptotic cysteine protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; FADD-homologous ICE/CED-3-like protease; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog
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