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- a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI)
Product short description
Price:
                                                                                    608 EUR
                                                                            
                                Size:
                                        1000ug
                                    
                                Catalog no.:
                                        GEN602022
                                    
                                Product detailed description
Concentration
                                        N/A
                                    
                                Immunoglobulin isotype
                                        IgG2b
                                    
                                Clone
                                        1.B.15
                                    
                                Source organism
                                        Ascites
                                    
                                Category
                                        Antibodies
                                    
                                Clonality
                                        Monoclonal
                                    
                                Also known as
                                        a1-Antitrypsin
                                    
                                Tested applications:
                                        ELISA (EL/EIA)
                                    
                                Subcategory
                                        Mnoclonal antibodies
                                    
                                Host organism
                                        Mouse (Mus musculus)
                                    
                                Purification method
                                        Affinity Purified by Protein A affinity chromatography.
                                    
                                Other gene names
                                        SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
                                    
                                Gene name synonims
                                        SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
                                    
                                Gene name
                                        SERPINA1; SERPINA1; PI; A1A; AAT; PI1; A1AT; PRO2275; alpha1AT; AAT; PI; SPAAT
                                    
                                Form/Appearance
                                        Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide, before the addition of glycerol to 40%.
                                    
                                Species reactivity
                                        Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
                                    
                                Specificity and cross-reactivity
                                        Recognizes human Alpha-1-Antitrypsin (AAT). No crossreactivity with alpha-1-acid glycoprotein, serum albumin or other serum proteins.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
                                    
                                Other names
                                        alpha-1-antitrypsin; Alpha-1-antitrypsin; alpha-1-antitrypsin; serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
                                    
                                Storage and shipping
                                        Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
                                    
                                Description
                                        The a1-Antitrypsin (AAT, alpha-1-AT, alpha1 Proteinase Inhibitor, alpha1 PI) is a α- or alpha protein sometimes glycoprotein present in blood.Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
                                    
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