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- MBS Monoclonals
- CD130 (gp130 Receptor, Oncostatin M-R, OSM-R, IL-6 Signal Transducer)
Product short description
Price:
707 EUR
Size:
100ug
Catalog no.:
GEN602318
Product detailed description
Concentration
N/A
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Other names
N/A
Immunoglobulin isotype
IgG1
Also known as
CD130
Clone
3H1837
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Tested applications:
ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Purification method
Highly Purified by Ion Exchange chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, before the addition of glycerol to 40%.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes soluble and membrane bound human gp130 receptor. This antibody has been reported to block the activity of IL-6.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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