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- MBS Monoclonals
- Caspase 8, p18 (FLICE, MACH, Mch5)
Product short description
Price:
685 EUR
Size:
100ug
Catalog no.:
GEN603159
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG2b
Clone
6D220
Category
Antibodies
Clonality
Monoclonal
Also known as
Caspase 8, p18
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Storage and shipping
Store the antibody at -20 degrees Celsius.
Tested applications:
Western Blot (WB), Immunoprecipitation (IP)
Purification method
Affinity 97% (SDS-PAGE)Epitope-affinity purified.
Other gene names
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Gene name synonims
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Gene name
CASP8; CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8; FLJ17672; MGC78473; MCH5
Form/Appearance
Supplied as a liquid in 0.15M PBS, pH 7.2, containing 1% BSA and 0.01% thimerosal.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Specificity and cross-reactivity
Recognizes human procaspase-8 and active human caspase-8. Detects procaspase-8 (p55/54), the intermediate cleavage products (p43/41) and the p18 active subunit of caspase-8 by Western blot. Does not recognize mouse caspase-8.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
Caspase-8; Caspase-8; caspase-8; FADD-like ICE; OTTHUMP00000163717; OTTHUMP00000163720; OTTHUMP00000165062; OTTHUMP00000165063; OTTHUMP00000165064; OTTHUMP00000206552; MACH-alpha-1/2/3 protein; apoptotic protease Mch-5; MACH-beta-1/2/3/4 protein; apoptotic cysteine protease; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; FADD-homologous ICE/CED-3-like protease; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog
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