FXR (Farnesoid X-activated Receptor, HRR-1, BAR, RIP14, NR1H4)

812 EUR

100ug

GEN603991

FXR

N/A

5L1

IgG2a

Antibodies

Monoclonal

fxr; fxr; fxr; N/A

fxr; fxr; fxr; N/A

fxr; fxr; fxr; N/A

Mnoclonal antibodies

Mouse (Mus musculus)

Human (Homo sapiens)

Purified by ammonium sulfate precipitation.

Supplied as a liquid in PBS, 0.1% sodium azide.

FXR; FXR; farnesoid X-activated receptor; farnesoid X-activated receptor; N/A

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes human FXR. Species Crossreactivity: rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.