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- AP2 Transcription Factor, alpha, beta (Clathrin Adaptor Protein Complex)
Product short description
Price:
641 EUR
Size:
100ug
Catalog no.:
GEN604278
Product detailed description
Concentration
N/A
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Immunoglobulin isotype
N/A
Clone
3H547
Category
Antibodies
Clonality
Monoclonal
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Subcategory
Mnoclonal antibodies
Also known as
AP2 Transcription Factor, alpha, beta
Storage and shipping
Store the antibody at -20 degrees Celsius.
Other names
AP2-like ethylene-responsive transcription factor; N/A
Purification method
Affinity Purified by Protein A affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Tested applications:
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes both the alpha and beta isoforms of AP-2.AP-2 is a transcription factor, part of the OB2 complex and has been shown to up regulate C-erb-B2 transcription.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The AP2 Transcription Factor, alpha, beta (Clathrin Adaptor Protein Complex) is a α- or alpha protein sometimes glycoprotein present in blood.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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