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- Epidermal Growth Factor Receptor, phosphorylated Receptor (Tyr1068) (EGFR, Epidermal Growth Factor Receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor precursor, ERBB, ERBB1, HER1, mENA, PIG61, Rece
Product short description
Price:
486 EUR
Size:
100ul
Catalog no.:
GEN632610
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
3i13
Virus
leukemia
Category
Antibodies
Clonality
Monoclonal
Purification method
Ascites Ascites
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Subcategory
Mnoclonal antibodies
Also known as
Epidermal Growth Factor Receptor Receptor
Other gene names
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Gene name synonims
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Gene name
EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1
Tested applications:
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Form/Appearance
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
Species reactivity
Human (Homo sapiens), Monkey, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity
Recognizes overexpressed levels of human EGF receptor only when phosphorylated at Tyr1068. Does not recognize other sites of tyrosine phosphorylation on EGF receptor, nor does it crossreact with other tyrosine-phosphorylated proteins. Species crossreactivity: rat and monkey.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
epidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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