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- MBS Monoclonals
- IgE, Heavy Chain (Biotin)
Product short description
Price:
746 EUR
Size:
500ug
Catalog no.:
GEN633284
Product detailed description
Additional isotype
IgE
Gene name
N/A
Concentration
N/A
Gene name synonims
N/A
Other gene names
N/A
Other names
N/A
Immunoglobulin isotype
IgG1
Clone
3H2284
Category
Antibodies
Clonality
Monoclonal
Conjugation
Biotinylated
Tested applications:
ELISA (EL/EIA)
Also known as
IgE, Heavy Chain
Subcategory
Mnoclonal antibodies
Source organism
Mouse (Mus musculus)
Host organism
Rat (Rattus norvegicus)
Storage and shipping
Store the antibody at -20 degrees Celsius.
Purification method
Affinity Purified by affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes the mouse epsilon immunoglobulin heavy chain and does not crossreact with other mouse immunoglobulin classes or subclasses.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
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