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- Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) (Biotin)
Product short description
Price:
724 EUR
Size:
100ug
Catalog no.:
GEN600440
Product detailed description
Concentration
N/A
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Other names
N/A
Immunoglobulin isotype
IgG
Clone
7C29
Category
Antibodies
Clonality
Monoclonal
Conjugation
Biotinylated
Tested applications:
ELISA (EL/EIA)
Source organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Host organism
Rat (Rattus norvegicus)
Also known as
Flk-1 Receptor Tyrosine Kinase
Purification method
Purified by immunoaffinity chromatography.
Form/Appearance
Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, before the addition of glycerol to 40%. Labeled with Biotin.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Specificity and cross-reactivity
Recognizes mouse FLK13-Mb. Reacts specifically with human FLK-1/VEGFR-2/KDR. No crossreactivity with VGFR-1/FLT-1 or FLT-4.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage, For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 6 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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