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- CD123 (IL-3 Receptor alpha, IL-3Ra)
Product short description
Price:
1232 EUR
Size:
0.25 miligrams
Catalog no.:
GEN601008
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Also known as
CD123
Clone
3H1835
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Gene name
cd123; N/A; N/A; N/A
Gene name synonims
cd123; N/A; N/A; N/A
Other gene names
cd123; N/A; N/A; N/A
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS 40% glycerol. No preservatives added.
Tested applications:
Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Other names
cell division cycle protein 123-like protein; N/A; cell division cycle protein 123-like protein; N/A; N/A
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity and cross-reactivity
Recognizes human IL-3 receptor alpha chain (CD123). Useful for monitoring expression of the receptor on activated endothelial cells, monocytes and eosinophils, sorting bone marrow progenitor cells and purification of basophils. Does not neutralize the activity of the IL-3 receptor alpha chain.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The CD123 (IL-3 Receptor alpha, IL-3Ra) is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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