c-erbB2, phosphorylated (Ser1113) (HER-2, neu Receptor)

768 EUR

100ug

GEN604225

N/A

N/A

N/A

N/A

N/A

N/A

IgG1

6D177

c-erbB2

Monoclonal

Antibodies

Mnoclonal antibodies

Mouse (Mus musculus)

ELISA (EL/EIA), Western Blot (WB)

Store the antibody at -20 degrees Celsius.

Chain P, Single Chain Fv Of C219 Heavy Chain V101l Mutant In Complex With Synthetic Epitope Peptide; N/A

Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes human and mouse c-erbB2 phosphorylated at Ser1113. Detects a band of ~180kD by Western Blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.