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- MBS Monoclonals
- c-Myc Oncoprotein Antibody
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438133
Product detailed description
Gene name
MYC
Gene name synonims
N/A
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Clone
CT14.G4
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Immunoglobulin isotype
IgG1, kappa
Also known as
c-Myc Oncoprotein
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
MYC; MYC; MRTL; MYCC; c-Myc; bHLHe39; BHLHE39; bHLHe39
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens), Chimpanzee, Gorilla. Does not react with Mouse (Mus musculus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
myc proto-oncogene protein; Myc proto-oncogene protein; myc proto-oncogene protein; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor; v-myc avian myelocytomatosis viral oncogene homolog; Class E basic helix-loop-helix protein 39; bHLHe39; Proto-oncogene c-Myc; Transcription factor p64
Specificity and cross-reactivity
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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