Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438175
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Concentration
N/A
Form/Appearance
N/A
Gene name
BCL2
Also known as
Bcl-2
French translation
anticorps
Clone
100/D5+124
Clonality
Monoclonal
Category
Antibodies
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Other gene names
BCL2; BCL2; Bcl-2; PPP1R50; N/A
Immunoglobulin isotype
IgG1, kappa (100/D5) + IgG1, kappa (124)
Tested applications:
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Other names
apoptosis regulator Bcl-2 alpha isoform; Apoptosis regulator Bcl-2; apoptosis regulator Bcl-2; protein phosphatase 1, regulatory subunit 50; B-cell CLL/lymphoma 2; N/A
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens). Does not react with Mouse (Mus musculus) and Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
This antibody recognizes a protein of 25-26kDa, identified as the bcl-2?lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of bcl-2?lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of bcl-2?lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express bcl-2 protein and the small number in which the neoplastic cells are bcl-2 negative.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.