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- MBS Monoclonals
- Heparin Binding EGF-like Growth Factor (HB-EGF, HBEGF, Diphtheria Toxin Receptor, DT-R, DTR) Antibody
Product short description
Price:
730 EUR
Size:
500ug
Catalog no.:
GEN603983
Product detailed description
Immunoglobulin isotype
IgG2a
Clone
7H229
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Concentration
~0.5 mg/ml (after reconstitution)
Also known as
Heparin Binding EGF-like Growth Factor
Tested applications:
ELISA (EL/EIA), Western Blot (WB), Neutralization
Other gene names
HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL
Gene name synonims
HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL
Gene name
HBEGF; HBEGF; DTR; DTS; DTSF; HEGFL; DTR; DTS; HEGFL
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
heparin-binding EGF-like growth factor; Proheparin-binding EGF-like growth factor; proheparin-binding EGF-like growth factor; OTTHUMP00000159876; heparin-binding epidermal growth factor; diphtheria toxin receptor (heparin-binding EGF-like growth factor); diphtheria toxin receptor (heparin-binding epidermal growth factor-like growth factor); heparin-binding EGF-like growth factor; Diphtheria toxin receptor
Specificity and cross-reactivity
Recognizes human Heparin Binding EGF-like Growth Factor (HB-EGF). Does not crossreact with recombinant human Amphiregulin, BTC, HRG-alpha, HRG-beta, EGF, TGF-alpha or recombinant mouse Epigen or Epiregulin.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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