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- MBS Monoclonals
- GCSFR (Granulocyte Colony-stimulating Factor Receptor, G-CSF Receptor, G-CSF-R, CD114, CSF3R) Antibody
Product short description
Price:
835 EUR
Size:
200ug
Catalog no.:
GEN609786
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Also known as
GCSFR
Clone
10K224
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Tissue
granulocyte
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Gene name
CSF3R; N/A; CD114; GCSFR; N/A
Gene name synonims
CSF3R; N/A; CD114; GCSFR; N/A
Other gene names
CSF3R; N/A; CD114; GCSFR; N/A
Purification method
Affinity Purified by Protein G affinity chromatography.
Tested applications:
ELISA (EL/EIA), Western Blot (WB), Gel Shift Assay (GS/EMSA)
Form/Appearance
Supplied as a lyophilized powder in 0.01M PBS, pH 7.2. Reconstitute with sterile dH20.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human G-CSFR. Does not react with MBP or BSA.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
granulocyte colony-stimulating factor receptor; Granulocyte colony-stimulating factor receptor; granulocyte colony-stimulating factor receptor; G-CSF-R; CD114 antigen; G-CSF receptor; OTTHUMP00000009703; OTTHUMP00000009704; OTTHUMP00000009705; colony stimulating factor 3 receptor (granulocyte); N/A
Gene
Granulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim.
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with sterile dH20. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
Colonies can be formed by stimulating factors or recombinant GM-CSF and CSFs activity expressed in Units compared to a standard.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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