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- Anti-Mouse CD120a (TNF-R, p55), PE (Clone HM104) (rat IgG2a)
Product short description
Price:
431 EUR
Size:
50ug
Catalog no.:
GEN520046
Product detailed description
Form/Appearance
PE
Other names
N/A
Purification method
N/A
Other gene names
N/A
Gene name synonims
N/A
Clone
HM104
Immunoglobulin isotype
Rat IgG2a
Category
Antibodies
Clonality
Monoclonal
Gene name
CD120a (TNF-R, p55)
Also known as
CD120a (TNF-R, p55)
Subcategory
Mnoclonal antibodies
Host organism
Rat (Rattus norvegicus)
Tested applications:
Immunohistochemistry (IHC)
Latin name
Mus musculus,Rattus norvegicus
Concentration
Antibody Concentration: 0.1 miligram per 1 mililiter
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Storage and shipping
Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. DO NOT FREEZE. Avoid prolonged exposure to light.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
CD120a (TNF-R, p55) (Mouse TNFR-p55); Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
About
Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Gene
Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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